Litcius/Paper detail

Engineering of l-threonine aldolase for the preparation of 4-(methylsulfonyl)phenylserine, an important intermediate for the synthesis of florfenicol and thiamphenicol

Zhicheng Liu, Xi Chen, Qijia Chen, Jinhui Feng, Min Wang, Qiaqing Wu, Dunming Zhu

2020Enzyme and Microbial Technology28 citationsDOI

Topics & Concepts

ChemistryAldolase AAldol reactionStereoselectivityMutantStereochemistryGlycineEnantiopure drugBiochemistryAmino acidEnzymeCatalysisEnantioselective synthesisGeneEnzyme Catalysis and ImmobilizationChemical Synthesis and AnalysisAnalytical Chemistry and Chromatography