Methionine restriction exposes a targetable redox vulnerability of triple-negative breast cancer cells by inducing thioredoxin reductase
Dmitry Malin, Yoonkyu Lee, Olga E. Chepikova, Elena Strekalova, Alexis Carlson, Vincent L. Cryns
Topics & Concepts
AuranofinGlutathioneThioredoxinThioredoxin reductaseGlutaredoxinCancer researchOxidative stressTriple-negative breast cancerTXNIPCancer cellBiologyMSRAMethionineChemistryBiochemistryCancerImmunologyBreast cancerEnzymeAmino acidRheumatoid arthritisGeneticsRedox biology and oxidative stressCancer Research and TreatmentsSulfur Compounds in Biology