Splenectomy enhances the Ly6Clow phenotype in hepatic macrophages by activating the ERK1/2 pathway during liver fibrosis
Zhongqiang Zheng, Huan Wang, Liang Li, Shaoying Zhang, Chunyan Zhang, Hailong Zhang, Fanpu Ji, Xi Liu, Kai Zhu, Guangyao Kong, Zongfang Li
Topics & Concepts
FibrosisSplenectomyMacrophageSpleenPhenotypeHepatic fibrosisInflammationMedicineIn vivoIntraperitoneal injectionPathologyCCL4Cancer researchImmunologyBiologyChemistryCarbon tetrachlorideInternal medicineIn vitroGeneBiochemistryBiotechnologyOrganic chemistryLiver physiology and pathologyHepatocellular Carcinoma Treatment and PrognosisOrgan Transplantation Techniques and Outcomes