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A mitochondria-targeted near-infrared fluorescent probe for detecting H<sub>2</sub>S, Cys, and GSH simultaneously in tumors

Miaomiao Zhang, Ying Yang, Zijuan Hai, Shusheng Zhang, Bin Zhao

2025Chemical Communications8 citationsDOI

Abstract

In this study, we developed a mitochondria-targeted near-infrared fluorescent probe HD-Br-D for simultaneous detection of H 2 S, Cys, and GSH in vitro and in vivo .

Topics & Concepts

FluorescenceGlutathioneMitochondrionIn vivoChemistryIn vitroInfraredBiophysicsCysteineMolecular biologyBiochemistryBiologyEnzymeOpticsGeneticsPhysicsSulfur Compounds in BiologyEicosanoids and Hypertension PharmacologyNeuroscience of respiration and sleep
A mitochondria-targeted near-infrared fluorescent probe for detecting H<sub>2</sub>S, Cys, and GSH simultaneously in tumors | Litcius