An efficient synthesis of highly substituted functionalized pyrroles via a four-component coupling reaction catalyzed by Fe(III)-Schiff base/SBA-15
Ghasem Rezanejade Bardajee, Aseyeh Ghaedi, Hamideh Hazrati, Farnaz Jafarpour
Abstract
An environmentally friendly, straightforward, and cheap synthesis of highly substituted functionalized pyrrole derivatives via one pot four-component reactions of 1,3-dicarbonyl compounds, amines, aromatic aldehydes, and nitroalkanes have been developed. This methodology provides desired pyrroles in good-to-excellent yields in the presence of Fe (III)-Schiff base/SBA-15 as a heterogeneous catalyst.
Topics & Concepts
CatalysisSchiff basePyrroleChemistryComponent (thermodynamics)Base (topology)Environmentally friendlyCombinatorial chemistryCoupling reactionOrganic chemistryReaction conditionsPolymer chemistryMathematicsThermodynamicsEcologyMathematical analysisBiologyPhysicsSynthesis and Characterization of PyrrolesPorphyrin and Phthalocyanine ChemistryMulticomponent Synthesis of Heterocycles