Oridonin ameliorates caspase-9-mediated brain neuronal apoptosis in mouse with ischemic stroke by inhibiting RIPK3-mediated mitophagy
Lei Li, Jingjing Song, Mengxue Zhang, Huiwen Zhang, Haiyan Zhu, Wei Guo, Cailong Pan, Xue Liu, Lu Xu, Zhiyuan Zhang
Topics & Concepts
NeuroprotectionMitophagyApoptosisPharmacologyGene knockdownProgrammed cell deathCaspase 3IschemiaIn vivoMedicineReperfusion injuryBiologyChemistryInternal medicineBiochemistryAutophagyBiotechnologyBioactive Natural Diterpenoids ResearchAutophagy in Disease and TherapyCell death mechanisms and regulation