Effects of high fructose corn syrup on intestinal microbiota structure and obesity in mice
Xiaorong Wang, Liying Zhu, Xiaoqiong Li, Xin Wang, Ruirong Hao, Jinjun Li
Abstract
High fructose corn syrup (HFCS)-associated health problems have raised concerns. We investigated the effects of HFCS-containing drinking water on body fat, intestinal microbiota structure of mice, and the relationships between them. HFCS drinking water significantly increased body fat content and altered the intestinal microbiome. The Christensenellaceae R-7 group negatively correlated with body weight, perirenal fat, epididymal fat, and liver fat percentage.
Topics & Concepts
High-fructose corn syrupCorn syrupFructoseFood scienceObesityMicrobiomeGut floraBiologyChemistryEndocrinologyBiochemistryBioinformaticsDiet, Metabolism, and DiseaseDiet and metabolism studiesGut microbiota and health