Molecular engineering of AIE-active boron clustoluminogens for enhanced boron neutron capture therapy
Wenli Ma, Yanyang Wang, Yilin Xue, Mengmeng Wang, Changsheng Lu, Guo Wanhua, Yuan‐Hao Liu, Diyun Shu, Guoqiang Shao, Qinfeng Xu, Deshuang Tu, Hong Yan
Abstract
. This study not only expands the application scopes of both AIE-active molecules and boron clusters, but also provides a new molecular engineering strategy for a deep-penetrating cancer therapeutic protocol based on BNCT.
Topics & Concepts
BoronNeutron captureCarboraneIn vivoLung cancerChemistryMaterials scienceMedicineOncologyStereochemistryOrganic chemistryBiologyBiotechnologyBoron Compounds in ChemistryRadiopharmaceutical Chemistry and ApplicationsBoron and Carbon Nanomaterials Research