Direct C(sp<sup>2</sup>)–H fluoroalkylation of quinoxalin-2(1<i>H</i>)-ones with (fluoroalkyl)triphenylphosphonium salts and alkenes
Wenwen Wang, Tong‐Hao Zhu, Jie Wu
Abstract
A photoredox-catalyzed direct C(sp 2 )–H fluoroalkylation of quinoxalin-2(1 H )-ones with (fluoroalkyl)triphenylphosphonium salts and alkenes is described, providing a practical approach for the generation of diverse fluoroalkyl-containing quinoxalin-2(1 H )-ones.
Topics & Concepts
ChemistryMedicinal chemistryOrganic chemistryFluorine in Organic ChemistrySynthesis and Biological Evaluation