Zinc catalysed C3–H borylation of indoles and 1,1-diboration of terminal alkynes
Binfeng Zhang, Youliang Zou, Li Wang, Hua Zhang
Abstract
-catalysed C3-H borylation of indoles with pinacolborane was developed. This transformation represents the use of an abundant, cheap and environmentally benign zinc catalyst in catalytic direct aromatic C-H borylation and offers a simple and prompt route towards the synthesis of C3-borylated indoles. The 1,1-diboration of terminal alkynes was also achieved using the same catalytic system to produce 1,1-diborylated alkenes.
Topics & Concepts
BorylationChemistryCatalysisZincCombinatorial chemistryOrganic chemistryAlkylArylOrganoboron and organosilicon chemistryCatalytic C–H Functionalization MethodsCatalytic Cross-Coupling Reactions