Nonquinolone Options for the Treatment of Mycoplasma genitalium in the Era of Increased Resistance
Michelle Doyle, Lenka A. Vodstrcil, Erica L. Plummer, Ivette Aguirre, Christopher K. Fairley, Catriona S. Bradshaw
Abstract
Abstract In the era of increasing macrolide- and quinolone-resistant Mycoplasma genitalium (MG), we report the efficacy of 2 nonquinolone antimicrobials in patients with limited treatment options. Pristinamycin + doxycycline cured 75% (95% CI, 64%–85%), and minocycline cured 71% (95% CI, 54%–85%) of cases. These data provide useful estimates to inform clinical practice.
Topics & Concepts
Mycoplasma genitaliumMedicineMinocyclineDoxycyclineQuinoloneAntimicrobialMycoplasmaMicrobiologyInternal medicineAzithromycinAntibioticsGynecologyChlamydia trachomatisBiologyReproductive tract infections researchBlood groups and transfusionGenital Health and Disease