Litcius/Paper detail

Approaching High-Accuracy Side Effect Prediction of Traditional Chinese Medicine Compound Prescription Using Network Embedding and Deep Learning

Zeheng Wang, Liang Li, Jing Yan, Yuanzhe Yao

2020IEEE Access22 citationsDOIOpen Access PDF

Abstract

In this paper, we realize high-accuracy side-effect prediction of Traditional Chinese Medicine Compound Prescription by introducing network embedding and deep learning. A random walk network that could efficiently interpret the information in the prescription is established from a conventional Bag-of-Word network. After the validation of this random walk network, the highest prediction accuracy reaches 0.908 where a simple five-layer artificial neural network is implemented, rendering this method is promising for Traditional Chinese Medicine side-effect prediction and other medicines with a similar structure such as the compound drugs.

Topics & Concepts

Computer scienceArtificial intelligenceMedical prescriptionArtificial neural networkEmbeddingDeep learningRendering (computer graphics)Traditional Chinese medicineWord embeddingRandom forestMachine learningRandom walkData miningMedicineMathematicsStatisticsAlternative medicinePharmacologyPathologyTraditional Chinese Medicine StudiesTraditional Chinese Medicine AnalysisMetabolomics and Mass Spectrometry Studies