Inflamed Ulcerative Colitis Regions Associated With MRGPRX2-Mediated Mast Cell Degranulation and Cell Activation Modules, Defining a New Therapeutic Target
Ernie Chen, Ling-Shiang Chuang, Mamta Giri, Nicole Villaverde, Nai-Yun Hsu, Ksenija Sabic, Sari Joshowitz, Kyle Gettler, Shikha Nayar, Zhi Chai, Isaac L. Alter, Colleen Chasteau, Ujunwa Korie, Siarhei Dzedzik, Tin Htwe Thin, Aayushee Jain, Arden Moscati, Gerardus Bongers, Richard H. Duerr, Mark S. Silverberg, Steven R. Brant, John D. Rioux, Inga Peter, L. Philip Schumm, Talin Haritunians, Dermot McGovern, Yuval Itan, Judy H. Cho
Topics & Concepts
BiologyDegranulationMast cellCell biologyMolecular biologySignal transductionImmunologyReceptorBiochemistryMast cells and histamineReceptor Mechanisms and SignalingPhosphodiesterase function and regulation