Overview of oral tolerance induction for prevention of food allergy—Where are we now?
Marta Krawiec, Helen R. Fisher, George Du Toit, Henry T. Bahnson, Gideon Lack
Abstract
Oral tolerance induction through early introduction of allergenic food has proven effective in randomized controlled trials. This new approach to weaning has been incorporated into many national and international infants' feeding guidelines. However, there are questions that require further discussion, such as, which foods should be introduced early, should the intervention be targeted to infants at high-risk or to the general population, and what is the ideal timing for early food introduction. This review examines the extent to which recent trials address these critical questions and highlights areas where further research is required.
Topics & Concepts
Food allergyMedicineOral toleranceIntervention (counseling)Oral food challengeWeaningPopulationRandomized controlled trialIntensive care medicineAllergyPediatricsEnvironmental healthImmunologySurgeryInternal medicinePsychiatryImmune systemFood Allergy and Anaphylaxis ResearchAsthma and respiratory diseasesEosinophilic Esophagitis