The influence of an enamine usnic acid derivative (a tyrosyl-DNA phosphodiesterase 1 inhibitor) on the therapeutic effect of topotecan against transplanted tumors in vivo
В. П. Николин, Н. А. Попова, В. И. Каледин, Olga A. Luzina, А. Л. Захаренко, Нариман Ф. Салахутдинов, Olga I. Lavrik
Topics & Concepts
TopoisomeraseEnamineTopotecanChemistryUsnic acidIn vivoDNAPharmacologyDNA damageCancer researchBiochemistryBiologyChemotherapyGeneticsBotanyLichenCatalysisCancer therapeutics and mechanismsCancer Treatment and PharmacologySynthesis and bioactivity of alkaloids