Acute Kidney Injury in Cardiogenic Shock: An Updated Narrative Review
Sohrab Singh, Ardaas Kanwar, Pranathi R. Sundaragiri, Wisit Cheungpasitporn, Alexander G. Truesdell, S. Tanveer Rab, Mandeep Singh, Saraschandra Vallabhajosyula
Abstract
Acute myocardial infarction with cardiogenic shock (AMI-CS) is associated with high mortality and morbidity despite advancements in cardiovascular care. AMI-CS is associated with multiorgan failure of non-cardiac organ systems. Acute kidney injury (AKI) is frequently seen in patients with AMI-CS and is associated with worse mortality and outcomes compared to those without. The pathogenesis of AMI-CS associated with AKI may involve more factors than previously understood. Early use of renal replacement therapies, management of comorbid conditions and judicious fluid administration may help improve outcomes. In this review, we seek to address the etiology, pathophysiology, management, and outcomes of AKI complicating AMI-CS.