Best practice considerations for nonclinical in vivo cardiovascular telemetry studies in non-rodent species: Delivering high quality QTc data to support ICH E14/S7B Q&As

Eric I. Rossman, Todd Wisialowski, Hugo M. Vargas, Jean‐Pierre Valentin, Michael G. Rolf, Brian Roche, Steve Riley, Michael K. Pugsley, Jill V. Nichols, Dingzhou Li, Derek J. Leishman, Robert Kleiman, Andrea Greiter‐Wilke, Gary A. Gintant, Michael J. Engwall, Annie Delaunois, Simon Authier

2023Journal of Pharmacological and Toxicological Methods34 citationsDOI

Topics & Concepts

QT intervalhERGSafety pharmacologyMedicineGuidelineProtocol (science)HarmonizationPharmacologyClinical PracticeDrugAnesthesiaInternal medicineAlternative medicineFamily medicinePathologyPotassium channelPhysicsAcousticsCardiac electrophysiology and arrhythmiasComputational Drug Discovery MethodsStatistical Methods in Clinical Trials

Best practice considerations for nonclinical in vivo cardiovascular telemetry studies in non-rodent species: Delivering high quality QTc data to support ICH E14/S7B Q&amp;As

Topics & Concepts

Best practice considerations for nonclinical in vivo cardiovascular telemetry studies in non-rodent species: Delivering high quality QTc data to support ICH E14/S7B Q&As