HOTTIP knockdown inhibits cell proliferation and migration via regulating miR-490-3p/HMGB1 axis and PI3K-AKT signaling pathway in ox-LDL-induced VSMCs
Xiaoyan Guo, Yuhao Liu, Xiaohui Zheng, Yan Han, Jiangtao Cheng
Topics & Concepts
Gene knockdownCell growthVascular smooth musclePI3K/AKT/mTOR pathwayChemistryCancer researchMolecular biologyDownregulation and upregulationCell migrationCellProtein kinase BSignal transductionCell biologyBiologyApoptosisEndocrinologyBiochemistryGeneSmooth muscleCancer-related molecular mechanisms researchAdvanced Glycation End Products researchAtherosclerosis and Cardiovascular Diseases