Long-distance modulation of bystander tumor cells by CD8+ T-cell-secreted IFN-γ
Mirjam E. Hoekstra, Laura Bornes, Feline E. Dijkgraaf, Daisy Philips, Iris N. Pardieck, Mireille Toebes, Daniela S. Thommen, Jacco van Rheenen, Ton N. Schumacher
Topics & Concepts
Bystander effectCytotoxic T cellCD8Cell biologyEffectorAntigen presentationBiologyTumor antigenTumor microenvironmentImmune systemAntigenAntigen-presenting cellT cellImmunotherapyCancer researchIn vitroImmunologyBiochemistryCancer Immunotherapy and BiomarkersImmunotherapy and Immune ResponsesImmune Cell Function and Interaction