Lithium Dicyclohexylamide in Transition-Metal-Free Fischer–Tropsch Chemistry
Maotong Xu, Zheng‐Wang Qu, Stefan Grimme, Douglas W. Stephan
Abstract
Lithium dicyclohexylamide (Cy2NLi) reacts with syn-gas or CO to generate transient intermediates with carbene character, which are capable of reacting further with CO or H2, effecting sequential C–C and C–H bond formations from CO or H2, thus providing a transition-metal-free avenue to the fundamental reactions of the Fischer–Tropsch process. Further experimental and computational data indicate that reactions with CO and H2 are thermodynamically accessible, with a kinetic bias toward CO homologation.
Topics & Concepts
ChemistryFischer–Tropsch processTransition metalLithium (medication)CarbeneMetalInorganic chemistryPhotochemistryOrganic chemistryCatalysisMedicineEndocrinologySelectivityAsymmetric Hydrogenation and CatalysisCarbon dioxide utilization in catalysisN-Heterocyclic Carbenes in Organic and Inorganic Chemistry