Increased pulse wave velocity in persons with spinal cord injury: the effect of the renin-angiotensin-aldosterone system
Caitlyn G. Katzelnick, Joseph P. Weir, Genevieve Pinto Zipp, Michael F. LaFountaine, William A. Bauman, Trevor A. Dyson‐Hudson, Jill M. Wecht
Abstract
Our novel findings suggest that increased arterial stiffness in individuals with SCI may be due to greater dependency on the RAAS to maintain hemodynamic stability during an orthostatic challenge. Asymptomatic orthostatic hypotension can occur in persons with SCI during transition from the supine to the seated position and during other upright activities of daily living; however, it is seldom addressed by clinicians.
Topics & Concepts
Orthostatic vital signsSupine positionMedicineAsymptomaticSpinal cord injuryArterial stiffnessRenin–angiotensin systemAldosteronePulse wave velocityCardiologyHemodynamicsInternal medicinePhysical medicine and rehabilitationSpinal cordBlood pressurePsychiatryCardiovascular Health and Disease PreventionCardiovascular Syncope and Autonomic DisordersHeart Rate Variability and Autonomic Control