Litcius/Paper detail

FGF-MAPK signaling regulates human deep-layer corticogenesis

Carlos W. Gantner, Cameron J. Hunt, Jonathan C. Niclis, Vanessa Penna, Stuart J. McDougall, Lachlan H. Thompson, Clare L. Parish

2021Stem Cell Reports34 citationsDOIOpen Access PDF

Abstract

neurons by repressing alternative laminar fates. Taken together, FGF/MAPK regulates the proliferative/neurogenic balance in deep-layer corticogenesis and provides a resource for generating layer-specific neurons for studying development and disease.

Topics & Concepts

BiologyCorticogenesisFibroblast growth factorMAPK/ERK pathwayLayer (electronics)Cell biologySignal transductionComputational biologyGeneticsGeneEmbryonic stem cellReceptorChemistryOrganic chemistryNeurogenesis and neuroplasticity mechanismsFibroblast Growth Factor ResearchPhagocytosis and Immune Regulation