Antibacterial activity of hydrophobicity modulated cationic polymers with enzyme and pH-responsiveness
Desoshree Ghosh, Sandeep Yadav, Sagar Bag, Amirul Islam Mallick, Priyadarsi De
Abstract
Lysine and fatty acid-tethered amphiphilic copolymers exhibited potent antibacterial activity against Gram-positive ( B. subtilis ) and Gram-negative ( E. coli ) bacteria with side chain degradability in the presence of an enzyme and pH.
Topics & Concepts
Cationic polymerizationAntibacterial activityPolymerMaterials scienceEnzymeChemistryPolymer chemistryOrganic chemistryComposite materialBacteriaBiologyGeneticsAntimicrobial agents and applicationsAntimicrobial Peptides and ActivitiesBiopolymer Synthesis and Applications