Synthesis of 1,3,4-oxadiazoles derivatives with antidepressant activity and their binding to the 5-HT<sub>1A</sub> receptor
Shiben Wang, Lin Qi, Hui Liu, Kang Lei, Xuekun Wang, Renmin Liu
Abstract
receptor. The physicochemical and pharmacokinetic properties of the target compounds were predicted using Discovery Studio 2019 and ChemBioDraw Ultra 14.
Topics & Concepts
Antidepressant5-HT receptorChemistryReceptorPharmacologyStereochemistryCombinatorial chemistrySerotoninNeuroscienceBiochemistryMedicinePsychologyHippocampusSynthesis and biological activityClick Chemistry and ApplicationsChemical Reactions and Mechanisms