Selectfluor and TBAX (Cl, Br) Mediated Oxidative Chlorination and Bromination of Olefins
Ziya Dağalan, Ramazan Koçak, Arif Daştan, Bilal Nişancı
Abstract
Herein, we report the first metal-free and molecular halogen reagent-free dihomohalogenation methodology by using Selectfluor as an oxidant and tetrabutylammonium bromide/chloride salts as a halogen source. This effective strategy provides various fluorine-free halogenated products easily in quantitative yields from alkenes, alkynes, and natural products.
Topics & Concepts
SelectfluorChemistryHalogenationHalogenReagentBromideOrganic chemistryFluorineBromineCombinatorial chemistryAlkylVanadium and Halogenation ChemistryCatalytic C–H Functionalization MethodsOxidative Organic Chemistry Reactions