Development of curcumin-based amyloid β aggregation inhibitors for Alzheimer's disease using the SAR matrix approach
Rohmad Yudi Utomo, Yasunobu Asawa, Satoshi Okada, Hyun Seung Ban, Atsushi Yoshimori, Jürgen Bajorath, Hiroyuki Nakamura
Topics & Concepts
CurcuminChemistryCytotoxicityNeurotoxicityLead compoundStereochemistryStructure–activity relationshipBiochemistryIn vitroOrganic chemistryToxicityAlzheimer's disease research and treatmentsCurcumin's Biomedical ApplicationsCholinesterase and Neurodegenerative Diseases