Targeting cancer cells in acidosis with conjugates between the carnitine palmitoyltransferase 1 inhibitor etomoxir and pH (low) insertion peptides
Marine Deskeuvre, Junjie Lan, Emeline Dierge, Joris Messens, Olivier Riant, Cyril Corbet, Olivier Féron, Raphaël Frédérick
Topics & Concepts
ConjugateChemistryPeptideCancer cellBiochemistryCarnitinePharmacologyProdrugCancerCancer researchBiologyInternal medicineMedicineMathematical analysisMathematicsCancer, Hypoxia, and MetabolismATP Synthase and ATPases ResearchCancer, Lipids, and Metabolism