T resident helper cells promote humoral responses in the lung
Nivedya Swarnalekha, David Schreiner, Ludivine C. Litzler, Saadia Iftikhar, Daniel Kirchmeier, Marco Künzli, Young Min Son, Jie Sun, Étori Aguiar Moreira, Carolyn G. King
Abstract
Analysis of CD4 + T cell heterogeneity in the lung uncovers a Bcl6-dependent subset that supports mucosal antibody production.
Topics & Concepts
LungImmunologyBCL6AntibodyBiologyT helper cellT cellB cellMedicineImmune systemInternal medicineGerminal centerImmune Cell Function and InteractionT-cell and B-cell ImmunologyIL-33, ST2, and ILC Pathways