The Catabolic System of Acetovanillone and Acetosyringone in <i>Sphingobium</i> sp. Strain SYK-6 Useful for Upgrading Aromatic Compounds Obtained through Chemical Lignin Depolymerization
Yudai Higuchi, Naofumi Kamimura, Hiroki Takenami, Yusei Kikuiri, Chieko Yasuta, Kenta Tanatani, Toru Shobuda, Yuichiro Otsuka, Masaya Nakamura, Tomonori Sonoki, Eiji Masai
Abstract
-hydroxybenzoic acid), and acetophenone-related compounds (acetovanillone, acetosyringone, and 4'-hydroxyacetophenone) are produced as major aromatic monomers. Also, base-catalyzed depolymerization of guaiacyl lignin resulted in vanillin, vanillic acid, guaiacol, and acetovanillone as primary aromatic monomers. To date, microbial catabolic systems of vanillin, vanillic acid, and guaiacol have been well characterized, and the production of value-added chemicals from them has also been explored. However, due to the lack of information on the microbial acetovanillone and acetosyringone catabolic system, chemical production from acetovanillone and acetosyringone has not been achieved. This study elucidated the acetovanillone/acetosyringone catabolic system and demonstrates the potential of using these genes for the production of value-added chemicals from these compounds.