Litcius/Paper detail

Viscoelastic blood coagulation testing system enabled by a non‐contact triboelectric angle sensor

Baocheng Wang, Xuelian Wei, Hanlin Zhou, Xiaole Cao, Enyang Zhang, Zhong Lin Wang, Zhiyi Wu

2023Exploration16 citationsDOIOpen Access PDF

Abstract

Abstract Thromboelastography (TEG) remains a convenient and effective viscoelastic blood coagulation testing device for guiding blood component transfusion and assessing the risk of thrombosis. Here, a TEG enabled by a non‐contact triboelectric angle sensor (NTAS) with a small size (∼7 cm 3 ) is developed for assessing the blood coagulation system. With the assistance of a superelastic torsion wire structure, the NTAS‐TEG realizes the detection of blood viscoelasticity. Benefiting from a grating and convex design, the NTAS holds a collection of compelling features, including accurate detection of rotation angles from −2.5° to 2.5°, high linearity ( R 2 = 0.999), and a resolution of 0.01°. Besides, the NTAS exhibits merits of low cost and simplified fabrication. Based on the NTAS‐TEG, a viscoelastic blood coagulation detection and analysis system is successfully constructed, which can provide a graph and parameters associated with clot initiation, formation, and stability for clinicians by using 0.36 mL of whole blood. The system not only validates the feasibility of the triboelectric coagulation testing sensor, but also further expands the application of triboelectric sensors in healthcare.

Topics & Concepts

Triboelectric effectViscoelasticityMaterials scienceCoagulationTorsion (gastropod)Biomedical engineeringThromboelastographyComposite materialMedicineSurgeryPsychiatryAdvanced Sensor and Energy Harvesting MaterialsMuscle activation and electromyography studiesNon-Invasive Vital Sign Monitoring