Thermal [3+2] cycloaddition reactions as most universal way for the effective preparation of five-membered nitrogen containing heterocycles
Jowita Kras, Mikołaj Sadowski, Karolina Zawadzińska, Roman Nagatsky, Przemysław Woliński, Karolina Kula, Agnieszka Łapczuk-Krygier
Abstract
The possibility of the construction of five-membered heterocycles, including single heteroatom or systems with two, three and four heteroatoms were critically reviewed based on the recent reports regarding to the [3+2] cycloaddition reactions. Almost all of analysed reaction are realized with high regio- and stereoselectivity.
Topics & Concepts
HeteroatomCycloadditionStereoselectivityChemistryNitrogenCombinatorial chemistryOrganic chemistryCatalysisRing (chemistry)Organic Chemistry Cycloaddition ReactionsSynthesis and Characterization of PyrrolesAsymmetric Synthesis and Catalysis