Iridium(III) complexes entrapped in liposomes trigger mitochondria-mediated apoptosis and GSDME-mediated pyroptosis
Huiwen Zhang, Xiaofei Liao, Xiaoyun Wu, Chuanling Shi, Yuanyuan Zhang, Yuhan Yuan, Wenlong Li, Jiawen Wang, Yunjun Liu
Topics & Concepts
ChemistryApoptosisCytotoxicityHeLaCytotoxic T cellMolecular biologyCancer cellCytochrome cIC50Mitochondrial permeability transition poreProgrammed cell deathBiochemistryIn vitroCancerBiologyGeneticsMetal complexes synthesis and propertiesCancer Mechanisms and TherapyCell death mechanisms and regulation