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Daphnetin triggers ROS-induced cell death and induces cytoprotective autophagy by modulating the AMPK/Akt/mTOR pathway in ovarian cancer

Xiaoye Fan, Min Xie, Feijie Zhao, Jiajia Li, Chang-qing Fan, Hao Zheng, Zhentong Wei, Xinxin Ci, Songling Zhang

2021Phytomedicine58 citationsDOI

Topics & Concepts

AutophagyPI3K/AKT/mTOR pathwayApoptosisCancer researchProtein kinase BAMPKViability assayOvarian cancerCell growthChemistryProgrammed cell deathCell biologyCancer cellBiologyCancerPhosphorylationBiochemistryProtein kinase AGeneticsAutophagy in Disease and TherapyCell death mechanisms and regulationBioactive Natural Diterpenoids Research
Daphnetin triggers ROS-induced cell death and induces cytoprotective autophagy by modulating the AMPK/Akt/mTOR pathway in ovarian cancer | Litcius