Hydroboration and reductive amination of ketones and aldehydes with HBpin by a bench stable Pd(<scp>ii</scp>)-catalyst
Shreya Mahato, Parveen Rawal, Ajitrao Devadkar, Mayank Joshi, Angshuman Roy Choudhury, Bhaskar Biswas, Puneet Gupta, Tarun K. Panda
Abstract
A Pd( ii ) complex catalysed hydroboration and reductive amination reaction of several aldehydes and ketones are reported. DFT-based computational study of the reaction mechanism unravels the dual role of HBpin in accomplishing the hydroboration reaction.
Topics & Concepts
HydroborationChemistryCatalysisReductive aminationLigand (biochemistry)Organic chemistryAminationCombinatorial chemistryMedicinal chemistryReceptorBiochemistryOrganoboron and organosilicon chemistryAsymmetric Hydrogenation and CatalysisChemical Synthesis and Reactions