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Dual roles of bisphosphines and epoxides: Rh-catalyzed highly chemoselective and diastereoselective (3 + 2) transannulations of 1,2,3-thiadiazoles with cyanoepoxides

Ziyang Dong, Cunzhi Chen, Jing Wang, Jiaxi Xu, Zhanhui Yang

2021Organic Chemistry Frontiers27 citationsDOI

Abstract

Dual roles of bisphosphines and epoxides are demonstrated in highly chemoselective and diastereoselective (3 + 2) transannulations.

Topics & Concepts

ThiadiazolesChemistryCatalysisDual (grammatical number)StereochemistryMedicinal chemistryCombinatorial chemistryOrganic chemistryLiteratureArtCyclopropane Reaction MechanismsSynthesis and Catalytic ReactionsSynthetic Organic Chemistry Methods
Dual roles of bisphosphines and epoxides: Rh-catalyzed highly chemoselective and diastereoselective (3 + 2) transannulations of 1,2,3-thiadiazoles with cyanoepoxides | Litcius