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The new opportunities in medicinal chemistry of fourth-generation EGFR inhibitors to overcome C797S mutation

Jie He, Zhihui Zhou, Xin Sun, Zunhua Yang, Pengwu Zheng, Shan Xu, Wufu Zhu

2020European Journal of Medicinal Chemistry72 citationsDOIOpen Access PDF

Topics & Concepts

Epidermal growth factor receptorChemistryCancer researchMetastasisAngiogenesisCell growthEGFR inhibitorsLung cancerCancerPharmacologyReceptorInternal medicineMedicineBiochemistryLung Cancer Treatments and MutationsCancer therapeutics and mechanismsLung Cancer Research Studies
The new opportunities in medicinal chemistry of fourth-generation EGFR inhibitors to overcome C797S mutation | Litcius