Antimicrobial Activity of Peptide-Coupled Antisense Peptide Nucleic Acids in Streptococcus pneumoniae
Gina Barkowsky, Corina Abt, Irina Pöhner, Adam Bieda, Sven Hammerschmidt, Anette Jacob, Bernd Kreikemeyer, Nadja Patenge
Abstract
Streptococcus pneumoniae is the most common cause of community-acquired pneumonia and is responsible for the deaths of up to 2 million children each year. Antibiotic resistance and strain replacement by non-vaccine serotypes are growing problems.
Topics & Concepts
Streptococcus pneumoniaeMicrobiologyBiologyPeptide nucleic acidVirologyAntimicrobialNucleic acidPneumococcal infectionsAntibioticsBiochemistryRNA Interference and Gene DeliveryAntimicrobial Peptides and ActivitiesAdvanced biosensing and bioanalysis techniques