New Palladium(II) and Platinum(II) Complexes Based on Pyrrole Schiff Bases: Synthesis, Characterization, X-ray Structure, and Anticancer Activity
Simon N. Mbugua, Nicole Remaliah Samantha Sibuyi, Lydia W. Njenga, Ruth A. Odhiambo, Shem O. Wandiga, Mervin Meyer, Roger A. Lalancette, Martin O. Onani
Abstract
complex also demonstrated remarkably high selectivity with no cytotoxic activity toward the noncancerous breast cell line but reduced the viability of the five cancerous cell lines, which included one breast cancer cell line, by more than 60%. Further studies are required to evaluate the selective toxicity of these two complexes and to fully understand their mechanism of action.
Topics & Concepts
ChemistryMonoclinic crystal systemStereochemistryTriclinic crystal systemHeLaMolar conductivitySchiff basePalladiumCrystallographyCrystal structureMetalCellBiochemistryOrganic chemistryCatalysisMetal complexes synthesis and propertiesFerrocene Chemistry and ApplicationsMagnetism in coordination complexes