The past, present, and future of artificial zinc finger proteins: design strategies and chemical and biological applications
Shigeru Negi, Miki Imanishi, Mami Hamori, Yuka Kawahara‐Nakagawa, Wataru Nomura, Kanae Kishi, Nobuhito Shibata, Yukio Sugiura
Topics & Concepts
Zinc fingerZincLIM domainChemistryComputational biologyZinc finger nucleaseRING finger domainProteomeHuman proteome projectBiochemistryGeneProteomicsBiologyOrganic chemistryTranscription factorRNA and protein synthesis mechanismsCRISPR and Genetic EngineeringAdvanced biosensing and bioanalysis techniques