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Subarachnoid hemorrhage distinctively disrupts the glymphatic and meningeal lymphatic systems in beagles

Jiaqi Wang, Tao Lv, Jia Feng, Li Yang, Weiwei Ma, Zhipeng Xiao, Weifeng Yu, Heng Zhao, Xiaohua Zhang, Qin Hu

2024Theranostics20 citationsDOIOpen Access PDF

Abstract

SAH impaired both glymphatic and meningeal lymphatic functions in beagles, with better restoration of lymphatic function post-SAH, which may contribute to functional recovery after SAH. External CSF drain is an effective therapeutic approach to facilitate the recovery of glymphatic and meningeal lymphatic function following SAH.

Topics & Concepts

Glymphatic systemLymphatic systemSubarachnoid hemorrhagePathologyMedicineNeuroscienceCerebrospinal fluidAnesthesiaPsychologyNeuroscience of respiration and sleepCerebrospinal fluid and hydrocephalusGenetic and Kidney Cyst Diseases