Access to benzene-modified 2<sup>nd</sup> generation strigolactams and GR24 by merging C–H olefination with decarboxylative Giese cyclization
Yuhua Ge, Xingyue Chen, Yi Dong, Hua-Nan Wang, Yangyan Li, Gang Chen
Abstract
Herein, we reported an efficient and general synthetic route to assemble benzene-modified 2 nd generation strigolactams and GR24. The key features of this synthesis include a palladium-catalyzed ortho -selective olefination and a decarboxylative Giese radical cyclization.
Topics & Concepts
ChemistryBenzeneOrobanchePhenylalanineCombinatorial chemistryStereochemistryOrganic chemistryGerminationBiochemistryBotanyAmino acidBiologyPlant Parasitism and ResistancePlant and animal studiesAllelopathy and phytotoxic interactions