Miniproteins may have a big impact: new therapeutics for autoimmune diseases and beyond
Nariaki Asada, Christian F. Krebs, Ulf Panzer
Abstract
In a landmark study recently published in Cell , Berger et al. demonstrated that computationally designed miniproteins could serve as novel, orally available treatment strategies by specifically targeting cytokine signaling pathways through the potent inhibition of ligand-receptor interactions in the body. 1 This breakthrough study unveils the potential for miniprotein-based therapies to revolutionize molecular treatment strategies for autoimmune diseases and cancers.
Topics & Concepts
MedicineImmunologyData scienceComputational biologyBiologyComputer scienceMonoclonal and Polyclonal Antibodies ResearchImmunodeficiency and Autoimmune DisordersImmunotherapy and Immune Responses