Fabrication of Nanofibrous/Xerogel Layer-by-Layer Biocomposite Scaffolds for Skin Tissue Regeneration: In Vitro Study
Fatma Elshishiny, Wael Mamdouh
Abstract
< 0.0001). A complete wound closure was observed in vitro in the presence of the three scaffold asymmetrical layers against the mouse embryonic fibroblast. The results of this study proved superior biological characteristics of the innovative asymmetrical composite that could further replace the burned or damaged skin layers with promising potential for clinical applications.
Topics & Concepts
BiocompatibilityMaterials scienceSwellingChitosanScaffoldBiomedical engineeringFibroblastBiocompositeDermal fibroblastExtracellular matrixElectrospinningWound healingPorosityChemical engineeringComposite materialChemistryComposite numberPolymerIn vitroOrganic chemistryBiochemistrySurgeryMetallurgyEngineeringMedicineElectrospun Nanofibers in Biomedical ApplicationsWound Healing and TreatmentsSilk-based biomaterials and applications