New cyclometalated gold (III) complex targeting thioredoxin reductase: exploring as cytotoxic agents and mechanistic insights
Fatemeh Abyar, Leila Tabrizi
Topics & Concepts
Thioredoxin reductaseChemistryReactive oxygen speciesCisplatinThioredoxinApoptosisDocking (animal)Cytotoxic T cellStereochemistryCysteineDNACancer cellBiochemistryCombinatorial chemistryEnzymeIn vitroBiologyCancerMedicineNursingChemotherapyGeneticsMetal complexes synthesis and propertiesSynthesis and Biological EvaluationFerrocene Chemistry and Applications