Component analysis and anti-pulmonary fibrosis effects of <i>Rosa sterilis</i> juice
Liqun Wang, Yali Li, Rui Xia, Xinyue Zheng, Xingjie Li, Shouxun Wu, Qianyu Zhang, Sha Li, Yuanle Deng, Yuqin Yao, Tinghong Ye, Wenya Yin
Abstract
High levels of flavonoids, polyphenols, and vitamin C may be the functional components of RSJ, and RSJ exerts anti-pulmonary fibrosis effects by reducing inflammation and inhibiting EMT and fibroblast differentiation through the Smad2/3 pathway.
Topics & Concepts
BleomycinPolyphenolChemistryPulmonary fibrosisFibrosisCatechinPotassiumFood scienceMyofibroblastAntioxidantBiochemistryBotanyBiologyPathologyMedicineChemotherapyGeneticsOrganic chemistryInterstitial Lung Diseases and Idiopathic Pulmonary FibrosisOccupational and environmental lung diseasesOccupational exposure and asthma