An Overview of Copper Nanoparticles: Synthesis, Characterisation and Anticancer Activity
Gowhar A. Naikoo, Fatema Al-Mashali, Fareeha Arshad, Naema AL-Maashani, Israr U. Hassan, Zamzam AL Baraami, Lukmanul H. Faruck, Ahsanulhaq Qurashi, Waqar Ahmed, Abdullah M. Asiri, Alaa A. A. Aljabali, Hamid A. Bakshi, Murtaza M. Tambuwala
Abstract
In this review, we summarised the different methods for copper nanoparticle synthesis, including green methods. We highlighted that the synthesis of the copper nanoparticles from green sources is preferable as they serve as stable and reducing entities. Furthermore, we critically reviewed the effectiveness of copper- based nanoparticles in oncogenic treatments emphasizing breast, lung, colorectal, and skin cancers. Finally, we have summarised the recent progress made in copper-based nanoparticles and their applications to amplify and rectify present cancer treatment options. The synthesis, characterization, stabilization, and functionalization techniques of various copper-based nanoparticles have also been highlighted in each section. In conclusion, the review provides the outlook of copper nanoparticles in cancer diagnostics and therapeutics.