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Venous thromboembolism in emergency general surgery patients: a single-centre retrospective cohort study

Mei Yang, Patrick Murphy, Laura Allen, Nathalie Sela, Shaylan K. Govind, Ken Leslie, Kelly Vogt

2020Canadian Journal of Surgery10 citationsDOIOpen Access PDF

Abstract

Background: There is limited literature on the risk of venous thromboembolism (VTE) in emergency general surgery (EGS) patients. We undertook this study to identify the rate of symptomatic VTE for patients undergoing EGS operations. Methods: We conducted a retrospective cohort study evaluating EGS patients who underwent operative intervention between March and December 2014. Data collected included patient demographics, type of procedure, risk of VTE, VTE prophylaxis, development of symptomatic VTE, and mortality. Results: We included 767 patients in our analysis. The mean age was 53 ± 19.7 years, and 52.2% of patients were female. Eighteen patients (2.3%) experienced VTE in hospital and 12 (1.6%) experienced VTE after discharge. Only 66% of patients received appropriate VTE prophylaxis. High-risk patients had a higher VTE rate (7.4% v. 2.3%, p < 0.001) and higher mortality (17.6% v. 4.0%, p < 0.001) than lowto moderate-risk patients. Conclusion: The risk of VTE in patients requiring EGS is significant and persists after hospital discharge. Further studies on quality improvement with VTE prophylaxis are warranted.

Topics & Concepts

MedicineVenous thromboembolismRetrospective cohort studyCohortDemographicsCohort studyEmergency medicineSurgeryInternal medicineThrombosisSociologyDemographyVenous Thromboembolism Diagnosis and ManagementBlood Coagulation and Thrombosis MechanismsCardiac, Anesthesia and Surgical Outcomes
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