Ammonium hydroxide as the ultimate amino source for the synthesis of <i>N</i>-unprotected 3-tetrasubstituted aminooxindoles <i>via</i> catalyst-free direct amination
Jing Yue, Xi‐Tao Ma, Xiong‐Li Liu, Xiong‐Li Liu, Jun‐Xin Wang, Xiongwei Liu, Xiongwei Liu, Ying Zhou
Abstract
The direct use of ammonium hydroxide in amination for the synthesis of primary amines is considered to be one of the major challenges in synthetic organic chemistry.
Topics & Concepts
AminationCatalysisChemistryAmmonium hydroxideAmmoniumHydroxideCombinatorial chemistryOrganic chemistryPolymer chemistryChemical Synthesis and AnalysisAsymmetric Hydrogenation and CatalysisSynthesis and Catalytic Reactions