Elucidating PAR1 as a therapeutic target for delayed traumatic brain injury: Unveiling the PPAR-γ/Nrf2/HO-1/GPX4 axis to suppress ferroptosis and alleviate NLRP3 inflammasome activation in rats
Amira A. El-Gazar, Ayman A. Soubh, Dalaal M. Abdallah, Ghada M. Ragab, Hanan S. El‐Abhar
Topics & Concepts
InflammasomeTraumatic brain injuryPeroxisome proliferator-activated receptorGPX4MedicinePharmacologyNeuroscienceChemistryCell biologyCancer researchBiologyReceptorInternal medicineOxidative stressPsychiatryGlutathione peroxidaseCatalaseFerroptosis and cancer prognosisInflammasome and immune disordersCancer-related molecular mechanisms research