A complement-microglial axis driving inhibitory synapse related protein loss might contribute to systemic inflammation-induced cognitive impairment
Shu‐Ming Li, Bin Li, Ling Zhang, Guang-Fen Zhang, Jie Sun, Mu‐Huo Ji, Jianjun Yang
Topics & Concepts
NeuroinflammationC5a receptorNeuroscienceInflammationSystemic inflammationComplement systemMicrogliaHippocampal formationInhibitory postsynaptic potentialReceptorBiologyInnate immune systemNeurodegenerationImmunologyImmune systemMedicineInternal medicineBiochemistryDiseaseNeuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatmentsS100 Proteins and Annexins